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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">healthcare</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение. Healthcare</journal-title><trans-title-group xml:lang="en"><trans-title>Healthcare</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-7218</issn><publisher><publisher-name>Republican Scientific and Practical Center for Medical Technologies, Informatization, Management and Health Economics</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">healthcare-148</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>В ПОМОЩЬ ПРАКТИЧЕСКОМУ ВРАЧУ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>AID OF THE PRACTICING PHYSICIAN</subject></subj-group></article-categories><title-group><article-title>Лихорадка неясного генеза в практике ревматолога</article-title><trans-title-group xml:lang="en"><trans-title>Fever of unknown origin in the practice of a rheumatologist</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Михневич</surname><given-names>Э. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mikhnevich</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Михневич Элеонора Анатольевна — д. м. н., доцент</p><p>Пр. Дзержинского, 83, 220116, г. Минск</p><p>Сл. тел. + 375 17 340-42-33</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Головко</surname><given-names>Т. Г.</given-names></name><name name-style="western" xml:lang="en"><surname>Golovko</surname><given-names>T. G.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мертвецов</surname><given-names>Е. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Mertvetsov</surname><given-names>E. A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Белорусский государственный медицинский университет</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>11-я городская клиническая больница</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2024</year></pub-date><pub-date pub-type="epub"><day>24</day><month>09</month><year>2025</year></pub-date><volume>0</volume><issue>9</issue><fpage>57</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Михневич Э.А., Головко Т.Г., Мертвецов Е.А., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Михневич Э.А., Головко Т.Г., Мертвецов Е.А.</copyright-holder><copyright-holder xml:lang="en">Mikhnevich E.A., Golovko T.G., Mertvetsov E.A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://healthcare.ejournal.by/jour/article/view/148">https://healthcare.ejournal.by/jour/article/view/148</self-uri><abstract><p>У пациентов с лихорадкой неясного генеза (ЛНГ) наиболее частыми причинами являются инфекции, менее частой причиной могут быть ревматические заболевания (РЗ) и онкопатология. Поэтому ревматологи периодически встречаются с этой проблемой, требующей детального обследования. Цель исследования. Изучить структуру диагностированных причин ЛНГ у пациентов ревматологического отделения, представить некоторые сложности при постановке диагноза с акцентом на РЗ. Материал и методы. Наблюдение за 85 пациентами, направленными в отделение ревматологии 11-й городской клинической больницы г. Минска с диагнозом ЛНГ или поставленным при поступлении в клинику как предварительный диагноз. Все пациенты проходили обследование соответственно действующим рекомендациям. Результаты. У пациентов наибольшее число составили случаи ЛНГ инфекционного генеза — 43 (50,6 %), онкогематологические заболевания с лихорадкой — 11 (16,5 %). У пациентов ревматологического профиля ЛНГ встречалась в дебюте: ревматоидный артрит — 6 (24 %) случаев, болезнь Стилла — 1 (4 %) случай, системная красная волчанка — 4 (16 %) случая, гистоновая волчанка — 2 (8 %) случая, системные васкулиты — 12 (48 %) случаев (гигантоклеточный васкулит — 3 (12 %), неспецифический аортоартериит — 1 (4 %), болезнь Бехчета — 1 (4 %), АНЦА-ассоциированные васкулиты — 7 (25 %)) — всего 25 (29,4 %) случаев. Другие причины ЛНГ составили 3 (3,5 %) случая. Представлены 5 (5,9 %) случаев периодонтитов, протекающих с лихорадкой, конусно-лицевая компьютерная томография (КЛКТ) позволила их выявить при негативных результатах ортопантомограммы. Проведен анализ диагностического поиска некоторых РЗ. Выводы. У пациентов ревматологического отделения с ЛНГ более половины случаев оказались инфекции — 43 (50,6 %) случая, РЗ составили 25 (29,4 %) случаев, на опухоли и другие причины пришлась меньшая доля случаев. Причиной ЛНГ могут быть периодонтиты, протекающие атипично, не всегда выявляемые при рентгенографии зубов, в сомнительных случаях целесообразно прибегать к КЛКТ. Данный вид томографии следует более активно включать в алгоритмы обследования пациентов с ЛНГ при неустановленной причине.</p></abstract><trans-abstract xml:lang="en"><p>Fever of unknown origin (FUO) is mostly due to infections, with rheumatic diseases (RD) and oncologic pathology being its fewer common causes. Rheumatologists periodically encounter this problem, which requires a thorough examination. Objective. To study the structure of diagnosed causes of FUO among patients of the Rheumatology Department and present some cases with difficulties in diagnosis with an emphasis on RD. Materials and methods. We observed 85 patients with a diagnosis of FUO referred to the Rheumatology Department (City Clinical Hospital № 11, Minsk). All patients were examined according to existing algorithms for FUO. Results. In the structure of FUO causes, infections accounted for 43 (50.6 %), oncological and hematological pathology with FUO was detected in 14 (16.5 %) of patients. Among patients with RD, FUO was observed at the onset of RA in 6 (24 %) cases, in Still’s disease — 1 (4 %), SLE — 4 (16 %), histone lupus — 2 (8 %), systemic vasculitis — 12 (48 %) (giant cell vasculitis — 3 (12 %), nonspecific aortoarteritis — 1 (4 %), Behcet’s disease — 1 (4 %), ANCA-associated vasculitis — 7 (25 %), in total 25 (29.4 %) cases. Other causes of FUO account for 3 (3.5 %). 5 (5.9 %) cases of periodontitis occurring with FUO are presented, in 2 cases cone beam computed tomography (CBCT) was made after excluding other infections and neoplasms, although dental radiography was negative. Some cases of RD were presented with diagnostic search analysis. Conclusion. In most patients admitted to the Rheumatology Department 50.6 % infections were found to be responsible for FUO. RD accounted for 29.4 %, and tumours and other causes made a smaller proportion. The periodontitis may be a cause of FUO that occurs atypically, not always routinely detected by dental radiography, therefore, CBCT is advisable. CBCT should be included in the algorithms for examining the patients with FUO without a unknown cause.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>лихорадка неясного генеза</kwd><kwd>ревматические заболевания</kwd><kwd>периодонтиты</kwd><kwd>алгоритм</kwd><kwd>конусно-лицевая компьютерная томография</kwd></kwd-group><kwd-group xml:lang="en"><kwd>fever of unknown origin</kwd><kwd>rheumatic diseases</kwd><kwd>periodontitis</kwd><kwd>algorithm</kwd><kwd>cone beam computed tomography</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Petersdorf, R. G. Fever of unexplained origin : report on 100 cases / R. G. Petersdorf, P. B. 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