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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">healthcare</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение. Healthcare</journal-title><trans-title-group xml:lang="en"><trans-title>Healthcare</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-7218</issn><publisher><publisher-name>Republican Scientific and Practical Center for Medical Technologies, Informatization, Management and Health Economics</publisher-name></publisher></journal-meta><article-meta><article-id custom-type="elpub" pub-id-type="custom">healthcare-197</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>ОБМЕН ОПЫТОМ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>EXCHANGE OF EXPERIENCE</subject></subj-group></article-categories><title-group><article-title>Клинико-патогистологическая диагностика потенциально злокачественных заболеваний и дисплазии эпителия полости рта: комплексный анализ и проблемные вопросы (на примере Минской области за период 2021—2023 гг.)</article-title><trans-title-group xml:lang="en"><trans-title>Clinical and pathohistologic diagnostics of oral potentially malignant disorders and oral dysplasia: complex analysis and problematic issues (on the Minsk region example for the period of 2021—2023)</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Бич</surname><given-names>Т. А.</given-names></name><name name-style="western" xml:lang="en"><surname>Bich</surname><given-names>T.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колядич</surname><given-names>Ж. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolyadich</surname><given-names>J.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Мириленко</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Mirilenko</surname><given-names>L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Поляков</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Polyakov</surname><given-names>S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Ефименко</surname><given-names>Н. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Efimenko</surname><given-names>N.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Кириленко</surname><given-names>С. Л.</given-names></name><name name-style="western" xml:lang="en"><surname>Kirilenko</surname><given-names>S.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Колячко</surname><given-names>И. И.</given-names></name><name name-style="western" xml:lang="en"><surname>Kolyachko</surname><given-names>I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-3"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Хонов</surname><given-names>В. Р.</given-names></name><name name-style="western" xml:lang="en"><surname>Khonov</surname><given-names>V.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Белорусский государственный медицинский университет</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>Республиканский научно-практический центр онкологии и медицинской радиологии им. Н. Н. Александрова</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-3"><institution>Минская областная стоматологическая поликлиника</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2025</year></pub-date><pub-date pub-type="epub"><day>17</day><month>10</month><year>2025</year></pub-date><volume>0</volume><issue>7</issue><elocation-id>57—67</elocation-id><permissions><copyright-statement>Copyright &amp;#x00A9; Бич Т.А., Колядич Ж.В., Мириленко Л.В., Поляков С.Л., Ефименко Н.Н., Кириленко С.Л., Колячко И.И., Хонов В.Р., 2025</copyright-statement><copyright-year>2025</copyright-year><copyright-holder xml:lang="ru">Бич Т.А., Колядич Ж.В., Мириленко Л.В., Поляков С.Л., Ефименко Н.Н., Кириленко С.Л., Колячко И.И., Хонов В.Р.</copyright-holder><copyright-holder xml:lang="en">Bich T., Kolyadich J., Mirilenko L., Polyakov S., Efimenko N., Kirilenko S., Kolyachko I., Khonov V.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://healthcare.ejournal.by/jour/article/view/197">https://healthcare.ejournal.by/jour/article/view/197</self-uri><abstract><p>Цель исследования. Провести комплексный анализ и оценить проблемные вопросы выявления потенциально злокачественных заболеваний и эпителиальной дисплазии полости рта на клиническом и патогистологическом этапах диагностики на примере Минской области за период 2021—2023 гг.Материал и методы. В исследование включены 185 пациентов УЗ «Минская областная стоматологическая поликлиника», которым выполнено патогистологическое исследование за период 2021—2023 гг. Методом сплошной выборки проведен анализ клинико-патогистологических данных с учетом возраста и пола пациентов, анатомо-топографической локализации патологического процесса, техники забора биопсийного материала, клинического диагноза и патогистологического заключения.Результаты. Доля пациентов с потенциально злокачественными заболеваниями полости рта, которым выполнена биопсия, составила 6,5 %. При направлении на патогистологическое исследование врачи-стоматологи в 21,5 % случаев неверно формулируют клинический диагноз, в 13,5 % случаев не указывают и в 75,1 % случаев неверно указывают технику забора биопсийного материала, в 15,7 % случаев не указывают анатомо-топографическую локализацию патологического процесса, что затрудняет интерпретацию выявленных морфологических изменений. Потенциально злокачественные заболевания морфологически верифицированы в 1,1 % случаев, дисплазия — в 1,6 % среди всех выполненных биопсий, составив по 16,7 % среди всех случаев, клинически определенных как потенциально злокачественные заболевания. В 30,8 % случаев всех биопсийных исследований и в 50,0 % случаев, клинически определенных как потенциально злокачественные заболевания, морфологический диагноз отсутствовал и был представлен описательным заключением в виде констатации имеющихся гистологических изменений.Заключение. Проведенный комплексный анализ выявил гиподиагностику потенциально злокачественных заболеваний полости рта как на клиническом, так и на морфологическом этапе. Обнаруженные проблемы при проведении патогистологического исследования среди врачей-стоматологов и врачей-патологоанатомов свидетельствуют о необходимости совершенствования профессиональной подготовки специалистов, занимающихся диагностикой заболеваний полости рта, а также разработки и внедрения требований к объему оказания медицинской помощи пациентам с потенциально злокачественными заболеваниями полости рта. </p></abstract><trans-abstract xml:lang="en"><p>Objective. To perform a comprehensive analysis and to assess the problematic issues in clinical and pathohistologic diagnostics of oral potentially malignant disorders end oral epithelial dysplasia on the Minsk Region example in the period of 2021—2023.Materials and methods. 185 patients underwent histopathologic examination between 2021 and 2023 from the MinskRegional Dental Polyclinic were included in the study. Clinical and histopathologic data were analyzed by the method of continuous selection, taking into the age and gender of patients, anatomical-topographical localization of the pathological process, technique of biopsy, clinical diagnosis and histopathologic report.Results. The rate of patients with oral potentially malignant disorders underwent a biopsy was 6.5 %. The dentists in 21.5 % of cases incorrectly formulate the clinical diagnosis, in 13.5 % of cases do not specify and in 75.1 % of cases incorrectly specify the technique of biopsy, in 15.7 % of cases do not mention the anatomical-topographical localization of the pathological process, thus complicating the interpretation of the revealed morphological changes during histopathological examination. Morphologically oral potentially malignant disorders were verified in 1.1 %, dysplasia — in 1,6 % of all performed biopsies and accounted each for 16.7 % of all cases clinically idenificated as oral potentially malignant disorders. In 30.8 % of all performed biopsies and in 50.0 % of clinically idenificated as oral potentially malignant disorders, the morphological diagnosis was absent and was provided as a descriptive conclusion in the form of present histologic changes announcement.Conclusion. The performed complex analysis revealed hypodiagnostics of oral potentially malignant disorders both at clinical and morphologic levels. Identified problematic issues in the diagnostic process among dentists and pathologists indicate the need to improve the professional training of specialists involved in the evaluation of oral cavity diseases, as well as the development and implementation of guidelines for medical care of patients with oral potentially malignant disorders.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>полость рта</kwd><kwd>потенциально злокачественные заболевания</kwd><kwd>лейкоплакия</kwd><kwd>плоский лишай</kwd><kwd>эпителиальная дисплазия</kwd><kwd>плоскоклеточная карцинома</kwd></kwd-group><kwd-group xml:lang="en"><kwd>oral potentially malignant disorders</kwd><kwd>oral leukoplakia</kwd><kwd>oral lichen planus</kwd><kwd>oral squamous cell carcinoma</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Survival probabilities and trends for lip, oral cavity and oropharynx cancers in Northern Portugal in the period 2000—2009 / L. 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