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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">healthcare</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение. Healthcare</journal-title><trans-title-group xml:lang="en"><trans-title>Healthcare</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-7218</issn><publisher><publisher-name>Republican Scientific and Practical Center for Medical Technologies, Informatization, Management and Health Economics</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.65249/1027-7218-2026-1-47-56</article-id><article-id custom-type="elpub" pub-id-type="custom">healthcare-241</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕПРЕРЫВНОЕ ПРОФЕССИОНАЛЬНОЕ РАЗВИТИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CONTINUOUS PROFESSIONAL DEVELOPMENT</subject></subj-group></article-categories><title-group><article-title>Функциональные болевые синдромы в практике врача – детского невролога: обзор литературы</article-title><trans-title-group xml:lang="en"><trans-title>Functional pain syndromes in the practice of a pediatric neurologist: a literature review</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Жевнеронок</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Zhaunyaronak</surname><given-names>I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Шалькевич</surname><given-names>Л. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Shalkevich</surname><given-names>L.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0007-6657-7434</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Сташков</surname><given-names>А. К.</given-names></name><name name-style="western" xml:lang="en"><surname>Stashkov</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Сташков Артем Константинович – врач – детский невролог</p><p>Ул. Володарского, 1, 220030, г. Минск</p><p>Сл. тел. +375 17 365-49-96</p></bio><xref ref-type="aff" rid="aff-2"/></contrib><contrib contrib-type="author" corresp="yes"><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Яковлев</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Yakovlev</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Минск</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Белорусский государственный медицинский университет</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>Минский городской детский клинический центр медицинской реабилитации</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>14</day><month>02</month><year>2026</year></pub-date><volume>0</volume><issue>1</issue><fpage>47</fpage><lpage>56</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Жевнеронок И.В., Шалькевич Л.В., Сташков А.К., Яковлев А.Н., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Жевнеронок И.В., Шалькевич Л.В., Сташков А.К., Яковлев А.Н.</copyright-holder><copyright-holder xml:lang="en">Zhaunyaronak I., Shalkevich L., Stashkov A., Yakovlev A.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://healthcare.ejournal.by/jour/article/view/241">https://healthcare.ejournal.by/jour/article/view/241</self-uri><abstract><p>Цель исследования. Проанализировать результаты исследований по определению основных дефиниций функциональных болевых синдромов в педиатрической практике и определить возможные подходы к ведению пациентов данной группы.Материал и методы. Поиск осуществляли в поисковых системах MEDLINE, PubMed, Google Scholar, eLIBRARY по тегам «функциональные неврологические расстройства», «дети», «болевой синдром», «головные боли», «неспецифические дорсалгии». Были отобраны публикации, относящиеся к обзорам литературы, рандомизированным контролируемым исследованиям, описаниям серий клинических случаев. Проанализировано 22 литературных источника с информацией, охватывающей временной интервал с 1970 по 2025 г.Результаты. Учитывая опыт зарубежных коллег, считаем, что в основе развития функциональных болевых синдромов лежат особенности психогенеза, рассматриваемые в контексте социопсихобиологической модели. Данная концепция учитывает ряд сложных нейробиологических когнитивных процессов, ответственных за перцепцию жизненных событий, функцию внимания к ним и собственным симптомам, а также мнестические функции, участвующие в формировании предшествующего опыта. Кроме того, модель включает сложные когнитивные процессы самопознания и самоконтроля, в том числе механизмы переживания значимости (значения и смысла) воспринимаемой информации. Мы также считаем, что в основе развития функциональных болевых синдромов лежит ряд генетических факторов, что подтверждается современными исследованиями.Заключение. Ключевым аспектом в ведении пациентов является исключение органического субстрата в развитии болевого синдрома, профилактическое воздействие с целью исключения хронизации процесса, а также релевантное и своевременное комплексное терапевтическое сопровождение, эффективность которого достигается посредством взаимодействия врачей-специалистов в составе мультидисциплинарных бригад с применением медикаментозных и немедикаментозных методик, а также поведенческой и когнитивно-поведенческой терапии.</p></abstract><trans-abstract xml:lang="en"><p>Objective. To analyze research findings on the primary definitions of functional pain syndromes in pediatric practice and to determine possible approaches for managing patients in this group.Materials and methods. The search was conducted using the MEDLINE, PubMed, Google Scholar, and eLIBRARY search engines with the keywords “functional neurological disorders,” “children,” “pain syndrome,” “headaches,” and “nonspecific dorsalgias”. Publications related to literature reviews, randomized controlled trials, and clinical case series descriptions were selected. A total of 22 literature sources covering the period from 1970 to 2025 were analyzed.Results. Based on the experience of foreign colleagues, it is considered that the development of functional pain syndromes is rooted in psychogenesis features, evaluated within the sociopsychobiological model. This concept accounts complex neurobiological cognitive processes responsible for the perception of life events, the function of attention to them and to one's own symptoms, as well as mnestic functions involved in forming previous experiences. Furthermore, the model incorporates complex cognitive processes of self-awareness and self-control, including mechanisms of experiencing the significance (meaning and sense) of perceived information. We also believe that a number of genetic factors underlie the development of functional pain syndromes, which is supported by current research.Conclusion. A key aspect in the management of patients is the exclusion of an organic substrate in the development of pain syndrome, preventive measures aimed at avoiding chronification, as well as relevant and timely comprehensive therapeutic support. The effectiveness is achieved through the interaction of medical specialists within multidisciplinary teams using both drug and nondrug methods, as well as behavioral and cognitive-behavioral therapy.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>функциональные неврологические расстройства</kwd><kwd>функциональный болевой синдром</kwd><kwd>клиника</kwd><kwd>диагностика</kwd><kwd>терапия</kwd><kwd>дети.</kwd></kwd-group><kwd-group xml:lang="en"><kwd>functional neurological disorders</kwd><kwd>functional pain syndrome</kwd><kwd>clinical presentation</kwd><kwd>diagnostics</kwd><kwd>therapy</kwd><kwd>children.</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Яхно, Н. Н. Боль : практическое руководство / под ред. акад. РАН Н. Н. Яхно. – М. : МЕДпресс-информ, 2022. – 416 с.</mixed-citation><mixed-citation xml:lang="en">Yakhno N.N. Pain. Moscow: MEDpress-inform; 2022. 416. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Functional neurological disorder: new subtypes and shared mechanisms / M. Hallett, S. Aybek, B.A. Dworetzky [et al.] // Lancet Neurology. – 2022. – Vol. 21, iss. 6. – P. 537–550.</mixed-citation><mixed-citation xml:lang="en">Hallett M., Aybek S., Dworetzky B.A., et al. Functional neurological disorder: new subtypes and shared mechanisms. Lancet Neurol. 2022; 21(6): 537–550.</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Дюкова, Г. М. Функциональные неврологические расстройства: диагностика и терапия / Г. М. Дюкова, В. Л. Голубев. – М. : МЕДпресс-информ, 2022. – 756 с.</mixed-citation><mixed-citation xml:lang="en">Dyukova G.M., Golubev V.L. Functional neurological disorders: diagnostics and therapy. Moscow: MEDpress-inform; 2022. 756. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Чутко, Л. С. Функциональные неврологические расстройства / Л. С. Чутко, С. Ю. Сурушкина // Журнал неврологии и психиатрии им. С. С. Корсакова. – 2021. – Т. 121, № 1. – С. 98–103.</mixed-citation><mixed-citation xml:lang="en">Chutko L.S, Surushkina S.Yu. Functional neurological disorders. Zhurnal nevrologii i psihiatrii im. S.S. Korsakova. 2021; 121(1): 98–103. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Функциональные расстройства в практике врача первичного звена / Е. Ю. Эбзеева, О. Д. Остроумова, Н. А. Плотникова [и др.] // Медицинский совет. – 2025. – Т. 19, № 6. – С. 214–220.</mixed-citation><mixed-citation xml:lang="en">Ebzeeva E.Yu., Ostroumova O.D., Plotnikova N.А., et al. Functional disorders in primary care physician practice. Medicinskij sovet. 2025; 19(6): 214–220. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Functional neurological disorder in children and young people: incidence, clinical features, and prognosis / K. Yong, R. F. M. Chin, J. Shetty [et al.] // Developmental Medicine &amp; Child Neurology. – 2023. – Vol. 65, № 9. – P. 1238–1246.</mixed-citation><mixed-citation xml:lang="en">Yong K., Chin R.F.M., Shetty J., et al. Functional neurological disorder in children and young people: incidence, clinical features, and prognosis. Dev Med Child Neurol. 2023; 65(9): 1238–1246.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Pain and functional neurological disorder : a systematic review and meta-analysis / M. Steinruecke, I. Mason, M. Keen [et al.] // Journal of Neurology, neurosurgery, and psychiatry. – 2024. – Vol. 95, № 9. – P. 874–885.</mixed-citation><mixed-citation xml:lang="en">Steinruecke M., Mason I., Keen M., et al. Pain and functional neurological disorder. J Neurol Neurosurg Psychiatry. 2024; 95(9): 874–885.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Functional neurological disorder – old problem new perspective / R.-S. Perjoc, E. Roza, O. A. Vladacenco [et al.] // International journal of environmental research and public health. – 2023. – Vol. 20, № 2. – doi: 10.3390/ijerph20021099.</mixed-citation><mixed-citation xml:lang="en">Perjoc R.S., Roza E., Vladacenco O.A., et al. Functional neurological disorder-old problem new perspective. Int J Environ Res Public Health. 2023; 20(2). doi: 10.3390/ijerph20021099.</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">The role of genetic polymorphisms in chronic pain patients / N. N. Knezevic T. Tverdohleb, I. Knezevic, K. D. Candido // International Journal of Molecular Sciences. – 2018. – Vol. 19, № 6. – doi: 10.3390/ijms19061707.</mixed-citation><mixed-citation xml:lang="en">Knezevic N.N., Tverdohleb T., Knezevic I., Candido K.D. The role of genetic polymorphisms in chronic pain patients. Int J Mol Sci. 2018; 19(6). doi: 10.3390/ijms19061707.</mixed-citation></citation-alternatives></ref><ref id="cit10"><label>10</label><citation-alternatives><mixed-citation xml:lang="ru">SLC45A4 is a pain gene encoding a neuronal polyamine transporter / S. J. Middleton, S. Markusson, M. Akerlund [et al.] // Nature. – 2025. – Vol. 646, № 8084. – P. 404–412.</mixed-citation><mixed-citation xml:lang="en">Middleton S.J., Markusson S., Akerlund M., et al. SLC45A4 is a pain gene encoding a neuronal polyamine transporter. Nature. 2025; 646(8084): 404–412.</mixed-citation></citation-alternatives></ref><ref id="cit11"><label>11</label><citation-alternatives><mixed-citation xml:lang="ru">Kozlowska, K. Recent advances in understanding the neurobiology of pediatric functional neurological disorder / K. Kozlowska, S. Scher // Expert Review of Neurotherapeutics. – 2024. – Vol. 24, № 5. – P. 497–516.</mixed-citation><mixed-citation xml:lang="en">Kozlowska K., Scher S. Recent advances in understanding the neurobiology of pediatric functional neurological disorder. Expert Rev Neurother. 2024; 24(5): 497–516.</mixed-citation></citation-alternatives></ref><ref id="cit12"><label>12</label><citation-alternatives><mixed-citation xml:lang="ru">Understanding functional neurological disorder: recent insights and diagnostic challenges / I. Mavroudis, D. Kazis, F. Z. Kamal [et al.] // International Journal of Molecular Sciences. – 2024. – Vol. 25, № 8. – doi: 10.3390/ijms25084470.</mixed-citation><mixed-citation xml:lang="en">Mavroudis I., Kazis D., Kamal F.Z., et al. Understanding functional neurological disorder: recent insights and diagnostic challenges. Int J Mol Sci. 2024; 25(8). doi: 10.3390/ijms25084470.</mixed-citation></citation-alternatives></ref><ref id="cit13"><label>13</label><citation-alternatives><mixed-citation xml:lang="ru">Espay, A. J. Current concepts in diagnosis and treatment of functional neurological disorders / A. J. Espay, S. Aybek, A. Carson [et al.] // JAMA Neurology. – 2018. – Vol. 75, № 9. – P. 1132–1141.</mixed-citation><mixed-citation xml:lang="en">Espay A.J., Aybek S., Carson A., et al. Current Concepts in Diagnosis and Treatment of Functional Neurological Disorders. JAMA Neurol. 2018; 75(9): 1132–1141.</mixed-citation></citation-alternatives></ref><ref id="cit14"><label>14</label><citation-alternatives><mixed-citation xml:lang="ru">A practical review of functional neurological disorder (FND) for the general physician / K. Bennett, C. Diamond, I. Hoeritzauer [et al.] // Clinical Medicine (London). – 2021. – Vol. 21, № 1. – P. 28–36.</mixed-citation><mixed-citation xml:lang="en">Bennett K., Diamond C., Hoeritzauer I., et al. A practical review of functional neurological disorder (FND) for the general physician. Clin Med (Lond). 2021; 21(1): 28–36.</mixed-citation></citation-alternatives></ref><ref id="cit15"><label>15</label><citation-alternatives><mixed-citation xml:lang="ru">A new science of emotion: implications for functional neurological disorder / J. Jungilligens, S. Paredes-Echeverri, S. Popkirov [et al.] // Brain. – 2022. – Vol. 145, № 8. – P. 2648–2663.</mixed-citation><mixed-citation xml:lang="en">Jungilligens J., Paredes-Echeverri S., Popkirov S., et al. A new science of emotion: implications for functional neurological disorder. Brain. 2022; 145(8): 2648–2663.</mixed-citation></citation-alternatives></ref><ref id="cit16"><label>16</label><citation-alternatives><mixed-citation xml:lang="ru">Functional neurological disorder in the emergency department / S. A. Finkelstein, M. A. Cortel-LeBlanc, A. Cortel-LeBlanc, J. Stone // Academic Emergency Medicine. – 2021. – Vol. 28, № 6. – P. 685–696.</mixed-citation><mixed-citation xml:lang="en">Finkelstein S.A., Cortel-LeBlanc M.A., Cortel-LeBlanc A., Stone J. Functional neurological disorder in the emergency department. Acad Emerg Med. 2021; 28(6): 685–696.</mixed-citation></citation-alternatives></ref><ref id="cit17"><label>17</label><citation-alternatives><mixed-citation xml:lang="ru">A framework for understanding the pathophysiology of functional neurological disorder / D. L. Drane, N. Fani, M. Hallett [et al.] // CNS Spectrums. – 2020. – Vol. 25. – P. 1–7.</mixed-citation><mixed-citation xml:lang="en">Drane D.L., Fani N., Hallett M., et al. A framework for understanding the pathophysiology of functional neurological disorder. CNS Spectr. 2020: 1–7.</mixed-citation></citation-alternatives></ref><ref id="cit18"><label>18</label><citation-alternatives><mixed-citation xml:lang="ru">Aybek, S. Diagnosis and management of functional neurological disorder / S. Aybek, D. L. Perez // British Medical Journal. – 2022. – Vol. 24. – doi: 10.1136/bmj.o64.</mixed-citation><mixed-citation xml:lang="en">Aybek S., Perez D.L. Diagnosis and management of functional neurological disorder. BMJ. 2022; 24. doi: 10.1136/bmj.o64.</mixed-citation></citation-alternatives></ref><ref id="cit19"><label>19</label><citation-alternatives><mixed-citation xml:lang="ru">Шалькевич, Л. В. Астения в педиатрической практике: взгляд невролога / Л. В. Шалькевич, А. В. Малаш // Медицинские новости. – 2016. – № 9. – С. 5–9.</mixed-citation><mixed-citation xml:lang="en">Shalkevich L.V., Malash A.V. Asthenia in pediatric practice from the neurologist’s standpoint. Medicinskie novosti. 2016; 9: 5–9.</mixed-citation></citation-alternatives></ref><ref id="cit20"><label>20</label><citation-alternatives><mixed-citation xml:lang="ru">Management of functional neurological disorder / G. S. Gilmour, G. S. Gilmour, G. Nielsen, T. Teodoro [et al.] // Journal of Neurology. – 2020. – Vol. 267, № 7. – P. 2164–2172.</mixed-citation><mixed-citation xml:lang="en">Gilmour G.S., Nielsen G., Teodoro T., et al. Management of functional neurological disorder. J Neurol. 2020; 267(7): 2164–2172.</mixed-citation></citation-alternatives></ref><ref id="cit21"><label>21</label><citation-alternatives><mixed-citation xml:lang="ru">Andreasen, N. J. Neuropsychiatric complications in burn patients / N. J. Andreasen // International Journal of Psychiatry in Medicine. – 1974. – Vol. 5, № 2. – P. 161–171.</mixed-citation><mixed-citation xml:lang="en">Andreasen N.J. Neuropsychiatric complications in burn patients. Int J Psychiatry Med. 1974; 5(2): 161–171.</mixed-citation></citation-alternatives></ref><ref id="cit22"><label>22</label><citation-alternatives><mixed-citation xml:lang="ru">Шалькевич, Л. В. Принципы терапии болевого синдрома у детей с ортопедоневрологическими осложнениями спастических форм детского церебрального паралича / Л. В. Шалькевич, А. К. Сташков, А. Н. Яковлев // Современные перинатальные медицинские технологии в решении проблем демографической безопасности. – 2024. – Вып. 17. – С. 371–382.</mixed-citation><mixed-citation xml:lang="en">Shalkevich L.V., Stashkov A.K., Yakovlev A.N. Principles of the therapy of pain syndrome in children with orthopedoneurological complications of spastic forms of cerebral palsy. Sovremennye perinatal'nye medicinskie tekhnologii v reshenii problem demograficheskoj bezopasnosti. 2024; 17: 371–382. (in Russian)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
