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<article article-type="research-article" dtd-version="1.3" xmlns:mml="http://www.w3.org/1998/Math/MathML" xmlns:xlink="http://www.w3.org/1999/xlink" xmlns:xsi="http://www.w3.org/2001/XMLSchema-instance" xml:lang="ru"><front><journal-meta><journal-id journal-id-type="publisher-id">healthcare</journal-id><journal-title-group><journal-title xml:lang="ru">Здравоохранение. Healthcare</journal-title><trans-title-group xml:lang="en"><trans-title>Healthcare</trans-title></trans-title-group></journal-title-group><issn pub-type="ppub">1027-7218</issn><publisher><publisher-name>Republican Scientific and Practical Center for Medical Technologies, Informatization, Management and Health Economics</publisher-name></publisher></journal-meta><article-meta><article-id pub-id-type="doi">10.65249/1027-7218-2026-7-58-66</article-id><article-id custom-type="elpub" pub-id-type="custom">healthcare-323</article-id><article-categories><subj-group subj-group-type="heading"><subject>Research Article</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="ru"><subject>НЕПРЕРЫВНОЕ ПРОФЕССИОНАЛЬНОЕ РАЗВИТИЕ</subject></subj-group><subj-group subj-group-type="section-heading" xml:lang="en"><subject>CONTINUOUS PROFESSIONAL DEVELOPMENT</subject></subj-group></article-categories><title-group><article-title>Эмфизема легких: от молекулярных механизмов к персонализированной терапии</article-title><trans-title-group xml:lang="en"><trans-title>Pulmonary emphysema: from molecular mechanisms to personalized therapy</trans-title></trans-title-group></title-group><contrib-group><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0004-5000-5683</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лаптева</surname><given-names>И. М.</given-names></name><name name-style="western" xml:lang="en"><surname>Lapteva</surname><given-names>I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лаптева Ираида Михайловна – к. м. н., доцент кафедры пульмонологии, фтизиатрии, аллергологии и профпатологии с курсом повышения квалификации и переподготовки</p><p>Пр. Дзержинского, 83, 220083, г. Минск</p><p>Сл. тел. +375 17 366-21-35 </p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0009-6708-8290</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Лаптев</surname><given-names>А. Н.</given-names></name><name name-style="western" xml:lang="en"><surname>Laptev</surname><given-names>A.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Лаптев Анатолий Николаевич </p><p>Минск</p></bio><xref ref-type="aff" rid="aff-1"/></contrib><contrib contrib-type="author" corresp="yes"><contrib-id contrib-id-type="orcid">https://orcid.org/0009-0005-9053-558X</contrib-id><name-alternatives><name name-style="eastern" xml:lang="ru"><surname>Орлова</surname><given-names>И. В.</given-names></name><name name-style="western" xml:lang="en"><surname>Orlova</surname><given-names>I.</given-names></name></name-alternatives><bio xml:lang="ru"><p>Орлова Ирина Вячеславовна </p><p>Минск</p></bio><xref ref-type="aff" rid="aff-2"/></contrib></contrib-group><aff xml:lang="ru" id="aff-1"><institution>Белорусский государственный медицинский университет</institution><country>Belarus</country></aff><aff xml:lang="ru" id="aff-2"><institution>Республиканский научно-практический центр пульмонологии и фтизиатрии</institution><country>Belarus</country></aff><pub-date pub-type="collection"><year>2026</year></pub-date><pub-date pub-type="epub"><day>13</day><month>08</month><year>2026</year></pub-date><volume>1</volume><issue>7</issue><fpage>58</fpage><lpage>66</lpage><permissions><copyright-statement>Copyright &amp;#x00A9; Лаптева И.М., Лаптев А.Н., Орлова И.В., 2026</copyright-statement><copyright-year>2026</copyright-year><copyright-holder xml:lang="ru">Лаптева И.М., Лаптев А.Н., Орлова И.В.</copyright-holder><copyright-holder xml:lang="en">Lapteva I., Laptev A., Orlova I.</copyright-holder><license xml:lang="ru" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>Данная работа распространяется под лицензией Creative Commons Attribution 4.0.</license-p></license><license xml:lang="en" license-type="creative-commons-attribution" xlink:href="https://creativecommons.org/licenses/by/4.0/" xlink:type="simple"><license-p>This work is licensed under a Creative Commons Attribution 4.0 License.</license-p></license></permissions><self-uri xlink:href="https://healthcare.ejournal.by/jour/article/view/323">https://healthcare.ejournal.by/jour/article/view/323</self-uri><abstract><p>Представлены современная дефиниция эмфиземы легких, алгоритмы диагностики и дифференциального диагноза, современные методы дифференцированного и оперативного лечения. Рассматривается роль реабилитационных и профилактических мероприятий в предотвращении инвалидизации пациентов с эмфиземой легких.</p></abstract><trans-abstract xml:lang="en"><p>This article presents a modern definition of pulmonary emphysema, diagnostic and modern methods of differentiated and surgical treatment. The role of rehabilitation and preventive measures in preventing the development of a disability in patients with pulmonary emphysema is discussed.</p></trans-abstract><kwd-group xml:lang="ru"><kwd>эмфизема</kwd><kwd>диагностика</kwd><kwd>дифференциальная диагностика</kwd><kwd>лечение</kwd><kwd>реабилитация</kwd><kwd>профилактика</kwd></kwd-group><kwd-group xml:lang="en"><kwd>emphysema</kwd><kwd>diagnosis</kwd><kwd>differential diagnosis</kwd><kwd>treatment</kwd><kwd>rehabilitation</kwd><kwd>prevention</kwd></kwd-group></article-meta></front><back><ref-list><title>References</title><ref id="cit1"><label>1</label><citation-alternatives><mixed-citation xml:lang="ru">Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (2026 Report) // Global Initiative for Chronic Obstructive Lung Disease. – URL: https://goldcopd.org/wp-content/uploads/2026/01/GOLD-REPORT-2026-v1.3-8Dec2025_WMV2.pdf (date of access: 19.07.2026).</mixed-citation><mixed-citation xml:lang="en">Global Initiative for Chronic Obstructive Lung Disease. Global strategy for the diagnosis, management, and prevention of chronic obstructive pulmonary disease (2026 Report). Available at: https://goldcopd.org/wp-content/uploads/2026/01/GOLD-REPORT-2026-v1.3-8Dec2025_WMV2.pdf (accessed: 19.07.2026).</mixed-citation></citation-alternatives></ref><ref id="cit2"><label>2</label><citation-alternatives><mixed-citation xml:lang="ru">Частота встречаемости признаков эмфиземы легких в протоколах рентгенографии и компьютерной томографии / Л. Н. Арзамасова, Ю. А. Васильев, А. В. Владзимирский, К. М. Арзамасов // Менеджер здравоохранения. – 2026. – № 5. – С. 85–95.</mixed-citation><mixed-citation xml:lang="en">Arzamasova L.N., Vasil'ev Y.A., Vladzimirskijy A.V., Arzamasov K.M. Pulmonary emphysema prevalence according to radiography and computed tomography. Menedzher zdravoohraneniya. 2026; 5: 85–95. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit3"><label>3</label><citation-alternatives><mixed-citation xml:lang="ru">Дефицит альфа-1-антитрипсина у взрослых / Российское респираторное общество. – М., 2017. – URL: https://spulmo.ru/download/Rekomend_Antitripsin.pdf (дата обращения: 19.07.2026).</mixed-citation><mixed-citation xml:lang="en">Russian Respiratory Society. Alpha-1-antitrypsin deficiency in adults. – Moscow; 2017. Available at: https://spulmo.ru/download/Rekomend_Antitripsin.pdf (accessed: 19.07.2026). (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit4"><label>4</label><citation-alternatives><mixed-citation xml:lang="ru">Новый алгоритм начальной и последующей терапии хронической обструктивной болезни легких / С. Н. Авдеев, З. Р. Айсанов, И. В. Лещенко, А. С. Белевский // Пульмонология. – 2026. – Т. 36, № 1. – С. 95–106.</mixed-citation><mixed-citation xml:lang="en">Avdeev S.N., Ajsanov Z.R., Leshсhenko I.V., Belevskij A.S. New algorithm for initial and subsequent therapy of chronic obstructive pulmonary disease. Pul'monologiya. 2026; 36(1): 95–106. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit5"><label>5</label><citation-alternatives><mixed-citation xml:lang="ru">Гольдштейн, В. Д. Эмфизема легких в клинической практике / В. Д. Гольдштейн. – М. : БИНОМ, 2016. – 176 с.</mixed-citation><mixed-citation xml:lang="en">Gol'dshtejn V.D. Pulmonary emphysema in clinical practice. Moscow: BINOM; 2016. 176. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit6"><label>6</label><citation-alternatives><mixed-citation xml:lang="ru">Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community : the MESA lung study / E. A. Hermann, A. Motahari, E. A. Hoffman, et al. // Thorax. – 2025. – Vol. 80, № 5. – P. 309–317.</mixed-citation><mixed-citation xml:lang="en">Hermann E.A., Motahari A., Hoffman E.A., et al. Associations of pulmonary microvascular blood volume with per cent emphysema and CT emphysema subtypes in the community. Thorax. 2025; 80(5): 309–317.</mixed-citation></citation-alternatives></ref><ref id="cit7"><label>7</label><citation-alternatives><mixed-citation xml:lang="ru">Lung volume reduction therapies in patients with emphysema : a systematic review and network meta-analysis / Liyan Bo, Xu He, Yan Chen [et al.] // Journal of Chronic Obstructive Pulmonary Disease. – 2025. – Vol. 22, № 1. – doi: 10.1080/15412555.2025.2567022.</mixed-citation><mixed-citation xml:lang="en">Liyan Bo, Xu He, Yan Chen, et al. Lung volume reduction therapies in patients with emphysema. COPD. 2025; 22(1). doi: 10.1080/15412555.2025.2567022.</mixed-citation></citation-alternatives></ref><ref id="cit8"><label>8</label><citation-alternatives><mixed-citation xml:lang="ru">Клинический случай длительной клапанной бронхоблокации при хронической обструктивной болезни легких / В. В. Плечев, А. М. Авзалетдинов, Р. Ф. Ганиев [и др.] // Креативная хирургия и онкология. – 2026. – Т. 16, № 1. – С. 81–89.</mixed-citation><mixed-citation xml:lang="en">Plechev V.V., Avzaletdinov A.M., Ganiev R.F., et al. Clinical case of prolonged endobronchial valve treatment in severe chronic obstructive pulmonary disease. Kreativnaya hirurgiya i onkologiya. 2026; 16(1): 81–89. (in Russian)</mixed-citation></citation-alternatives></ref><ref id="cit9"><label>9</label><citation-alternatives><mixed-citation xml:lang="ru">Берикханов, З. Г. Методы лечения хронической обструктивной болезни и эмфиземы легких / З. Г. Берикханов, А. М. Николаев, В. Ю. Серегина // Хирургия. Журнал им. Н. И. Пирогова. – 2023. – № 9. – С. 79–85.</mixed-citation><mixed-citation xml:lang="en">Berikhanov Z.G., Nikolaev A.M., Seregina V.Yu. Treatment of chronic obstructive pulmonary disease and emphysema. Hirurgiya. Zhurnal im. N.I. Pirogova. 2023; (9): 79–85. (in Russian)</mixed-citation></citation-alternatives></ref></ref-list><fn-group><fn fn-type="conflict"><p>The authors declare that there are no conflicts of interest present.</p></fn></fn-group></back></article>
