Study of invasive hemodynamics during the use of extracorporeal autohemomagnetotherapy in the intraoperative period during coronary artery bypass grafting under artificial circulation

Objective. To study the parameters of invasive hemodynamics, investigated using PiCCO, Flow-Track technologies in patients with ischemic heart disease in the intraoperative period during coronary artery bypass grafting (CABG) under artificial circulation (AC) with extracorporeal autohemomagnetic therapy (EAHMT).

Materials and methods. All patients were divided into two groups. Group 1 (17 patients) included standard anesthesia for CABG under AC without the use of EAHMT. Group 2 (17 patients) included standard anesthesia for CABG under AC with the use of EAHMT. In patients of the two groups, the parameters of mean arterial pressure (MAP), dose of vasopressor support were assessed. In patients of group 2, the parameters of cardiac index (CI), cardiac output (CO), stroke volume index (SVI), stroke volume variability (SVV) were studied. The relative change in these parameters was calculated individually for each patient. Then, using Statistica 10 software (Statsoft Inc., USA), a descriptive analysis of the obtained data was performed (Me [25 %; 75 %]). The significance of the results was assessed using the dependent variables method with the nonparametric Wilcoxon test. When comparing independent groups with non-normal distribution of one or two quantitative variables, a nonparametric method was used — the Mann — Whitney U-test.

Results. When using EAHMT in addition to standard anesthesia, a statistically significant increase in MAP, CI, CO, SVI, SVV, as well as a relative change in these parameters were observed. A statistically significant decrease in vasopressor support was noted in group 2. A statistically significant increase in the duration of the operation was revealed in group 1.

Conclusions. The use of EAHMT improves key hemodynamic parameters and proves its effectiveness and safety in the intraoperative period during myocardial revascularization under AC conditions. It is worth noting a statistically significant decrease in vasopressor support.

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