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Tuberculous meningitis (clinical observation and evaluation Thwaites index, Lancet consensus)

Abstract

This article reviews the case of a 16-year-old adolescent patient with tuberculous meningitis (TM), who was admitted to the Republican Scientific and Practical Center for Pulmonology and Tuberculosis (RSPCPT) for 425 days. Thearticle aims to discuss the degree of likelihood and severity of NV in the same patient using diagnostic scales (Thwaites diagnostic index, 2002, Lancet Consensus System, 2010). The result on using of the diagnostic indexes shows high likelihood of TM in the patient. Clinical data also suggests the high severity of TM. The study highlights the need for use and development of more modern diagnostic methods and scales for the patients with suspected TM.

About the Authors

L. V. Litskevich
Белорусский государственный медицинский университет
Belarus


Zh. I. Kryvasheyeva
Белорусский государственный медицинский университет
Belarus


A. A. Astapov
Белорусский государственный медицинский университет
Russian Federation


O. M. Zalutskaya
РНПЦ пульмонологии и фтизиатрии
Belarus


N. K. Jha
Белорусский государственный медицинский университет
Belarus


S. Mazhar
Белорусский государственный медицинский университет
Belarus


References

1. Donovan J., Thwaites G. E., Huynh J. Tuberculous meningitis: where to from here? Curr. Opin. Infect. Dis. 2020. 33 (3): 259 66.

2. Pehlivanoglu F., Yasar K. K., Sengoz G. Tuberculous meningitis in adults: a review of 160 cases. Scientific World Journal. 2012; 2012: 169028.

3. Dr. Hari Kishan Boorugu, Dr. Varun Reddy, Dr. Arshad M Punjani (2020). Validation of Thwaites' Diagnostic Score in Adults with Tuberculous Meningitis. SAS Joumal of Medicine. 2020; 6: 166 -9.

4. Sulaiman T., Medi S., Erdem H. et al. The diagnostic utility of the «Thwaites' system» and «Lancet consensus scoring system» in tuberculous vs. non-tuberculous subacute and chronic meningitis: multicenter analysis of 395 adult patients. BMC Infect Dis. 2020; 20 (1): 788.

5. Thwaites G. E., Chau T. T. H., Stepniewska K. et al. Diagnosis of adult tuberculous meningitis by use of clinical and laboratory features. The Lancet. 2002; 360: 1287-92.

6. Marais S., Thwaites G., Schoeman J. F. etal. Tuberculous meningitis: a uniform case definition for use in clinical research. Lancet Infect Dis. 2010; 10: 803 -12.


Review

For citations:


Litskevich L.V., Kryvasheyeva Zh.I., Astapov A.A., Zalutskaya O.M., Jha N.K., Mazhar S. Tuberculous meningitis (clinical observation and evaluation Thwaites index, Lancet consensus). Healthcare. 2023;(12):53-59. (In Russ.)

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ISSN 1027-7218 (Print)