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Rare causes of anaphylaxis in children and adolescents and the relevance of diagnostics

Abstract

Based on modern literature data, a comprehensive analysis of the problem of rare causes of anaphylaxis in children and adolescents is provided. It is emphasized that this is a complex task in terms of diagnostics, which takes place in the work of a practicing physician. Many authors point out that doctors have insufficient knowledge of the clinical significance of rare causes of childhood anaphylaxis and call for a more indepth coverage of these issues. The article provides a detailed review of anaphylaxis associated with exercise, alpha-gal syndrome, oral storage mite anaphylaxis, mast cell activation syndrome, etc. Understanding the role of these unusual triggers is critical for physicians to ensure accurate diagnosis and effective treatment of childhood anaphylaxis, emphasizing the need to increase clinical awareness to improve treatment outcomes and enhance the quality of life of children and adolescents at risk for anaphylactic reactions. The information presented is of great practical importance for practicing physicians.

About the Authors

I. Vasilevski
Белорусский государственный медицинский университет
Belarus


A. Ruban
Институт биофизики и клеточной инженерии НАН Беларуси
Belarus


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Vasilevski I., Ruban A. Rare causes of anaphylaxis in children and adolescents and the relevance of diagnostics. Healthcare. 2025;(7):12—27. (In Russ.)

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