Prognostic risk factors for recurrence in patients with respiratory tuberculosis

Objective. To determine the prognostic risk factors for recurrence in patients with respiratory tuberculosis and quantify their impact.
Materials and methods. The study was based on data from 224 patients with respiratory tuberculosis of working age. For the first time, all patients were referred to the Minsk City Medical Rehabilitation Expert Commission to determine disability, and in difficult expert cases to the consultative and polyclinic department of the Russian National Research Center for Medical Examination and Rehabilitation to clarify the severity of existing disability, as well as the clinical and labor prognosis for the period from 2017 to 2024. The average age (SE) of patients in this cohort was 47.4 (0.71) years.
Results. In the course of the study, indicators were identified that have a statistically significant effect on the risk of disease recurrence in the study cohort of patients with respiratory tuberculosis. The risk of developing the disease increases statistically significantly in the presence of the following negative factors: male gender (OR = 2.33), age > 51 years (OR = 2.31), living in rural areas (OR = 3.27), basic level of education (OR = 1.96), social category – not working (OR = 5.81), the presence of professional technical education (OR = 7.5), harmful working conditions (OR = 1.79), low skill level (OR = 2.23), unskilled labor (OR = 4.12) and BMI < 22 kg/m² (OR = 2.17).
Сonclusion. The identified prognostic risk factors for recurrence in the study cohort of patients with respiratory tuberculosis will be used to assess their combined impact, build a mathematical model of their combined impact, and develop a comprehensive methodology for assessing the risk of recurrence in patients with respiratory tuberculosis.

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