Clinical features of emerging polycystic ovary syndrome in adolescence

Abstract

Objective. То study the characteristic clinical and diagnostic features in adolescent girls with various phenotypes of theemerging polycystic ovary syndrome.

Materials and methods. The study included 205 teenage girls aged 12-18 years. The main group consisted of159 girls with signs of PCOS and 46 healthy girls - the control group. Their questionnaires and clinical examination wereconducted.

Results. The most pronounced deviations in sexual development were revealed in the classical PCOS phenotype. Ingirls with disorders corresponding to the specified phenotype, an inversion of the development of secondary sexualcharacteristics was noted in 21 % of cases, in 42% - later telarche, in 18,4 % - later menarche. The sonographic criteriafor the emerging polycystic ovary syndrome are: increased ovarian volume, the presence of an echopositive stroma and alarge number of follicles of various diameters with an echopositive wall.

Conclusion. During the formation of the reproductive system, the following features of sexual development should betaken into account: aberration of the sequence of development of secondary sexual characteristics, early puberty, early orlate telarche, early or late age of menarche. The identification of these clinical signs is the premise for including such girlsinto the PCOS risk group in order to appropriately handle the reproductive function deviations at early stages of theirdevelopment.