Сorneal crosslinking with personalized excimer laser photoablation
Abstract
Objective. To develop a modified corneal crosslinking technique with personalized excimer laser photoablation and evaluate its effectiveness and safety.
Materials and methods. The study included 55 patients (64 eyes) with stage 1—3 keratoconus (Amsler — Krumeich classification) with confirmed progressive course. Depending on the type of surgical treatment performed, the patients were divided into 2 groups: Group 1 — 28 patients (31 eyes) who underwent corneal crosslinking with personalized excimer laser photoablation, according to our proposed technique, and Group 2 — 27 patients (33 eyes) who underwent corneal crosslinking according to the standard technique (the «Dresden Protocol»).
Results. The value of uncorrected visual acuity did not differ significantly between the groups throughout the entire observation period, and the best-corrected visual acuity was significantly higher from the first month in Group 1. The central corneal thickness was statistically greater in Group 1 starting from the 6th month after treatment, and the value of the minimum thickness did not differ significantly throughout the observation period. Maximum keratometry became significantly lower already from the 1st month after surgical treatment in Group 1, and remained so throughout the observation period. There were no postoperative complications in any group.
Conclusions. The proposed combined method of corneal crosslinking with excimer laser photoablation provides safe and effective treatment of keratoconus and has a stabilizing effect on the progressive nature of the disease. At the same time, due to the use of an excimer laser, the duration of corneal syndrome decreases, corneal irregularity decreases, and visual functions improve in the postoperative period, which leads to the fastest visual, professional and social rehabilitation of patients with keratoconus after corneal crosslinking.
About the Authors
L. Stolyarova
10-я городская клиническая больница
Belarus
Belarus
T. Imshanetskaya
ИПК и ПКЗ УО «Белорусский государственный медицинский университет»
Belarus
Belarus
D. Abelski
ООО «МедВайз» — Центр михрохирургии глаза VOKA
Belarus
Belarus
I. Zabarouski
10-я городская клиническая больница
Belarus
Belarus
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Review
For citations:
Stolyarova L., Imshanetskaya T., Abelski D., Zabarouski I. Сorneal crosslinking with personalized excimer laser photoablation. Healthcare. 2025;1(1):4—14. (In Russ.)
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